PALO ALTO, Calif. & WALTHAM, Mass.–(BUSINESS WIRE)–May 29, 2003–

Eight New Investments Made in Emerging Market Leaders Across

Communications, Security, Medical Device and Neuroscience Sectors

Advanced Technology Ventures (ATV), a leading bi-coastal venture capital firm with $1.5 billion under management, today announced that it has made new investments in eight emerging market leaders since the beginning of the year. The companies represent a cross-section of ATV’s technology and healthcare market focus and include Acme Packet, e-Security, Hypnion, Packet Design, RFco, TranS1 and Visage.

“With one of the most challenging investment environments hopefully behind us, ATV is optimistic and actively pursuing opportunities in select, high-growth markets across multiple technology and healthcare sectors,” said Jos Henkens, ATV general partner. “We’re investing in companies started by mature, seasoned entrepreneurs with real expertise and novel technologies that address proven market needs. The trends that drive innovation remain as strong as ever, and I expect we’ll continue to see strong deal flow in the coming quarters.”

Founded in 1979, ATV’s diversification across technology and healthcare sectors remains a cornerstone of its investment strategy. The firm’s experience investing through numerous market cycles has enabled it to create strong syndicate partnerships, develop deep domain expertise across various target sectors, and understand the requisite elements that help emerging companies achieve sustained market success.

ATV currently has additional new investments in the final stages of closing and expects to continue this momentum throughout 2003, with a primary focus on early-stage companies in its primary target markets: communications, IT infrastructure, software and services, and healthcare. With a proven track record in supporting companies from inception to market success, ATV continues to work closely with promising new ventures across a number of emerging, high-growth sectors including security, wireless, networking, medical devices and neuroscience.

Select new ATV investments include:

— Acme Packet – developer of session border controllers for

service providers delivering interactive communications across

IP network borders;

— e-Security – global provider of security event management

(SEM) software;

— Hypnion – neuroscience company developing a new class of

therapies for chronic, debilitating sleep disorders;

— Packet Design – provider of network appliances that extend the

routing control plane for enhancing the performance of IP

networks;

— RFco – developer of a new generation of radio frequency

semiconductor components;

— TranS1 – development-stage company focused on novel

percutaneous products and procedures to treat lower back pain;

— Visage – first company to enable wireless carriers and

consumer brands to outsource the creation of mobile virtual

network operators (MVNOs) in the United States.

Over its 24-year history, ATV has consistently ranked among the country’s top VC firms. Notable technology investments include Webline Communications (acquired by Cisco); Epigram (acquired by Broadcom); Docent, Inc.; Bermai, Inc.; Actel Corp.; Creedence; Tripwire, Inc.; UpShot Corp.; and Redline Networks, Inc. Select healthcare investments include Cytyc Corp.; Novoste; Hydra BioSciences, Inc.; Optobionics Inc.; and Microvention. ATV’s partners combine deep domain expertise and direct operational experience to strategically guide their portfolio companies to sustained market success. Additionally, ATV’s technology partners provide portfolio companies with world-class technical and marketing expertise in their respective industries.

About Advanced Technology Ventures

Founded in 1979, Advanced Technology Ventures (ATV) is a bi-coastal venture capital firm with more than $1.5 billion in capital under management. ATV works closely with entrepreneurial teams across several markets, including communications, IT infrastructure, software and services, and healthcare, to build emerging-growth business ventures into market leaders. For more information, visit www.atvcapital.com.